Brain Organization: Wiring Economy Works for the Large and Small
نویسنده
چکیده
The highest-resolution test to date of the wire minimization hypothesis has found that this principle works well for brain regions with a volume just over 400 μm(3). What is the wire minimization hypothesis, and why should anyone care about it?
منابع مشابه
Interneuron Diversity series: Circuit complexity and axon wiring economy of cortical interneurons.
The performance of the brain is constrained by wiring length and maintenance costs. The apparently inverse relationship between number of neurons in the various interneuron classes and the spatial extent of their axon trees suggests a mathematically definable organization, reminiscent of 'small-world' or scale-free networks observed in other complex systems. The wiring-economy-based classificat...
متن کاملWiring Economy of Pyramidal Cells in the Juvenile Rat Somatosensory Cortex
Ever since Cajal hypothesized that the structure of neurons is designed in such a way as to save space, time and matter, numerous researchers have analyzed wiring properties at different scales of brain organization. Here we test the hypothesis that individual pyramidal cells, the most abundant type of neuron in the cerebral cortex, optimize brain connectivity in terms of wiring length. In this...
متن کاملInsurer Optimal Asset Allocation in a Small and Closed Economy: The Case of Iran’s Social Security Organization
We seek to determine the optimal amount of the insurer’s investment in all types of assets for a small and closed economy. The goal is to detect the implications and contributions the risk seeker and risk aversion insurer commonly make and the effectiveness in the investment decision. Also, finding the optimum portfolio for each is the main goal of the present study. To this end, we adopted the...
متن کاملWiring Economy and Volume Exclusion Determine Neuronal Placement in the Drosophila Brain
Wiring economy has successfully explained the individual placement of neurons in simple nervous systems like that of Caenorhabditis elegans [1-3] and the locations of coarser structures like cortical areas in complex vertebrate brains [4]. However, it remains unclear whether wiring economy can explain the placement of individual neurons in brains larger than that of C. elegans. Indeed, given th...
متن کاملSynaptic Connectivity in Anatomically Realistic Neural Networks: Modeling and Visual Analysis
The structural organization of neural circuitry is an important determinant of brain function. Thus, knowing the brain’s wiring (the connectome) is key to understanding how it works. For example, understanding how sensory information is translated into behavior requires a comprehensive view of the microcircuits performing this translation at the level of individual neurons and synapses. Obtaini...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Current Biology
دوره 22 شماره
صفحات -
تاریخ انتشار 2012